- A murderer who slits the throats of victims.
- An unscrupulous, ruthless or unethical person.
- (uncountable) A three-player pocket billiards game where the object is to be the last player with at least one ball still on the table.
- Italian: tagliagole
- Russian: головоре́з
- Spanish: degollador
- Involving the cutting of throats
- Of or relating to a card game where everyone plays for him or herself rather than playing with a partner.
- He found that playing cutthroat Spades was much more difficult than playing with a partner.
- Ruthlessly competitive, dog-eat-dog
- Law is a cutthroat business, you always have to look out to see who is trying to outdo you.