From Middle English noysom; equivalent to noy + -some (short for annoy, from an(n)oien, enoien from Anglo-Norman - anuier, from Old French enuier (French ennuyer), from Late Latin inodiare, from in- + odium ("hate")).

• IPA: /ˈnɔɪ.səm/

noisome

1. (literary) Morally hurtful or noxious.
2. (literary) Hurtful or noxious to health; unwholesome, insalubrious.

   Synonyms: Thesaurus:harmful

   • 1611, The Holy Bible, […] (King James Version), London: […] Robert Barker, […], →OCLC ↗, Psalms 91:3 ↗:

     Surely he shall deliuer thee from the snare of the fouler: and from the noisome pestilence.

3. (literary) Offensive to the senses; disgusting, unpleasant, nauseous, especially having an undesirable smell.

   Synonyms: foul, fetid, sickening, nauseating

   • 1598–1599 (first performance), William Shakespeare, “Much Adoe about Nothing”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […] (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, →OCLC ↗, [Act V, scene i], page 120 ↗:

     Foule words is but foule wind, and foule wind is but foule breath, and foule breath is noiſome, therefore I will depart vnkist.

   • 1731, [Jonathan Swift], “Strephon and Chloe”, in A Beautiful Young Nymph Going to Bed. […], Dublin, London: […] [William Bowyer] for J. Roberts […], published 1734, →OCLC ↗, page 8 ↗:

     And then, ſo nice, and ſo genteel; / Such Cleanlineſs from Head to Heel: / No Humours groſs, or frowzy Steams, / No noiſom Whiffs, or ſweaty Streams, / Before, behind, above, below, / Could from her taintleſs Body flow.

• French: désagréable, nuisible
• Russian: отврати́тельный

• French: nocif, insalubre, malsain, toxique
• German: ungesund, schädlich
• Italian: nocivo, insalubre, malsano
• Russian: вре́дный

• French: répugnant, dégoutant
• German: widerlich, ekelhaft, eklig
• Italian: disgustoso, repulsivo
• Russian: злово́нный