1. The act of perforating or the state of being perforated.
  2. Any opening in a solid object.
  3. (medicine) An abnormal opening in an organ, such as a rupture.
  4. A series of holes punched through something in order to assist in separating parts.
  5. (mathematics) That portion of a surface that remains after an open disk is removed from it.

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Offline English dictionary