unsex (unsexes, present participle unsexing; past and past participle unsexed)

1. To deprive of sexual attributes or characteristics.
   • 1603-06, William Shakespeare, Macbeth, Act I, Scene V:

     Lady Macbeth: "Come, you spirits / That tend on mortal thoughts! unsex me here, / And fill me from the crown to the toe full / Of direst cruelty:"

   • 1935 April, William Faulkner, “Skirmish at Sartoris”, in The Unvanquished, New York, N.Y.: Random House, published 1938, OCLC 1080149991 ↗; republished in The Unvanquished: The Corrected Text, New York, N.Y.: Vintage Books, October 1991, →ISBN, section 1, page 189 ↗:

     [S]he had expected the worst ever since Drusilla had deliberately tried to unsex herself by refusing to feel any natural grief at the death in battle not only of her affianced husband but of her own father [...]

2. To sterilize (deprive of the ability to procreate); to castrate.