• IPA: /æn.tæ.ɡə.ˈnɪs.tɪk/


  1. Contending or acting against.
    • They were distinct, adverse, even antagonistic.
    • 1866, American Journal of Pharmacy and the Sciences Supporting Public Health:
      Though the tephrosia is a powerful agent, and, if carried too far beyond the antagonistic action of the poison, is, I presume, not entirely without danger, I have never known any bad symptoms to arise from its use.
  2. (biochemistry) Relating to an antagonist
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